The submitting of the IND follows a successful Pre-IND meeting with the FDA dapoxetine-explained.html.

Collegium Pharmaceutical documents IND for second opioid item using DETERx technology Collegium Pharmaceutical, Inc dapoxetine-explained.html . The submitting of the IND follows a successful Pre-IND meeting with the FDA, during which guidance was offered to the Company regarding the foundation of acceptance and the product development plan.2 million new non-medical users aged 12 or old in 2008. The same publication also reported that the problem continues to grow in the US. From 2002 to 2008, the rate of current nonmedical usage of prescription pain relievers had improved among young adults aged 18 to 25. Extended discharge opioid formulations are appealing targets particularly for nonmedical use, because the time-release mechanism of most currently marketed products can be defeated by chewing, dissolving or crushing the formulation in drinking water, rendering the entire dose of drug instantly obtainable if ingested orally, snorted or injected. Predicated on the feedback obtained from the FDA in our Pre-IND conference, we believe that we have a clear understanding of the regulatory requirements essential for the approval of COL-172.?.

safety issue

College athletes smoke cigarettes marijuana for different reasons College athletes tend to be less likely than their non-athlete peers to smoke cigarettes marijuana. But when they do, they may have some different reasons for it, according to a study in the July issue of the Journal of Research on Drugs and alcohol. Past studies have shown that athletes generally smoke marijuana less frequently than other university students do. ‘But there continues to be a pretty large number who choose to use it,’ said Jennifer F. Buckman, Ph.D., of the guts of Alcohol Studies at Rutgers University in Piscataway, NJ. Because marijuana could have ill health effects-and perhaps hurt athletic performance-that begs the issue of why college sports athletes would use it, according to Buckman. Therefore for the new research, she and her co-workers surveyed 392 college sportsmen and 504 nonathlete students about marijuana make use of. Among guys, one-third of sports athletes said they’d used the medication during the past year, versus half of nonathletes; the same was true of 25 percent of woman sports athletes and 48 percent of nonathletes. Overall, athletes and non-athletes shared most of the same risk factors for marijuana use such as being white, being a smoke enthusiast and having an exaggerated perception of just how many of their peers utilize the drug. But there have been some differences too. ‘One thing that stood out is usually that sports athletes were much more likely to make use of marijuana because they believed it had been pleasurable,’ Buckman said. They were less likely, on the other hand, to use the drug for reasons like coping with stress. That shows that athletes largely smoke marijuana recreationally, than as a means of coping with life problems rather. The exception, though, may be male sportsmen who maintain using marijuana during their competitive season. The scholarly study found that these sports athletes reported more issues with anxiety and bad mood, and appeared more likely to use the drug for coping with stress weighed against the male sports athletes who prevented marijuana during their competitive time of year. Related StoriesNovel culturally-educated treatment benefits caregivers of people with schizophreniaNoninvasive CT scans greater than stress checks at spotting clogged arteriesStudy analyzes psychological stress of family members caregivers following Alzheimer's diagnosis’That is clearly a really interesting acquiring, and it’s a direction for analysis to go later on,’ Buckman said. ‘What are the stressors for these sports athletes? Is it academic? Is it the athletic competition?’ The ultimate goal in studies like these, Buckman observed, is to discover factors that seem to influence drug make use of, then develop specific text messages most likely to create a difference with a particular group. For example, she pointed to the finding that female learners with body-image worries were more likely to make use of marijuana than women without such concerns. As the study was done at onetime point, it isn’t clear which came initial: the marijuana use or the indegent body picture. But since marijuana established fact to cause the ‘munchies,’ and a yen for sweets particularly, it is possible that the drug use came first. Whatever the reason, college women-and specifically athletes who have to stay fit-might pay attention to anti-marijuana messages that emphasize the consequences on eating. More research are had a need to uncover the reason why that young people start using marijuana, despite the potential health and legal effects, according to Buckman. ‘This is a very commonly used medication,’ Buckman said, ‘and we simply need to understand even more about the factors that influence people to use it.’.

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